That's a street view of the Iroquois Hotel in Buffalo, NY around 1900. Pretty awesome picture, especially when you view it large and pick out the smaller surrounding details.
Looking at the lower right hand corner of the photo you find another building that housed a shoe store on the first floor, a Dentist office on the second floor, and a Photographer's Studio on the floor above that. "Tonalgia" was a pharmaceutical concoction popular back in the day. It contained Cocaine, and was one of several similar mixtures used to make dental work less of a terrifyingly painful affair.
Bliss Brothers photography studio saw lots of business in those days, I'm sure. Cabinet Card photos were all the rage at the turn of the century. It was common practice in those days for people to go into the photographer's studio and have their pictures made - often with props, pets, and their best clothing on display. A brief search of the internet produced this example:
Finding a picture of someone actually taken inside that studio in the photograph is one of the many things I love about the internet. It ain't all pron, silly videos, and politics out there :)